BEFIX Dry Syrup

BEFIX Dry Syrup is a third-generation oral cephalosporin antibiotic containing Cefixime, formulated for the effective treatment of a wide range of bacterial infections, especially in pediatric patients. BEFIX provides strong bactericidal action against susceptible Gram-positive and Gram-negative organisms and is well tolerated, making it a preferred choice in routine pediatric practice.

Indications and Clinical Use

BEFIX Dry Syrup is indicated for the treatment of:

• Upper respiratory tract infections (URTI)

• Lower respiratory tract infections (LRTI)

• Acute otitis media

• Tonsillitis and pharyngitis

• Sinusitis

• Urinary tract infections (UTIs)

• Typhoid fever

• Skin and soft tissue infections

• Other infections caused by Cefixime-sensitive organisms

Mechanism of Action

• Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), resulting in disruption of cell wall formation and bacterial cell death.

• It exhibits stability against many beta-lactamase-producing organisms, ensuring effective antibacterial activity.

This mechanism provides broad-spectrum, reliable bactericidal action with a low risk of resistance when used appropriately.

Dosage and Administration

• Dosage: As directed by the physician.

• Reconstitute the dry powder with boiled and cooled water up to the marked level.

• Shake well before each use.

• Dosage is based on the child’s age, body weight, and severity of infection.

• Complete the full prescribed course even if symptoms improve early.

Key Benefits of BEFIX Dry Syrup

• Broad-spectrum antibacterial coverage

• Effective in common pediatric infections

• Convenient once- or twice-daily dosing

• Well tolerated with proven safety profile

• Palatable flavor for better compliance in children

Adverse Effects and Safety Information

BEFIX Dry Syrup is generally well tolerated.

• Mild gastrointestinal effects such as diarrhea, nausea, vomiting, or abdominal discomfort may occur.

• Rarely, allergic reactions like rash or itching may be seen.

• Discontinue use and consult a physician if severe reactions occur.

Contraindications and Precautions

• Contraindicated in patients with known hypersensitivity to cephalosporins.

• Use with caution in patients with renal impairment or a history of gastrointestinal disease.

• Use only under medical supervision, especially in infants.

Drug Interactions

• May interact with anticoagulants, increasing bleeding risk.

• Inform the physician about all ongoing medications before starting BEFIX Dry Syrup.

Storage

• Store the dry powder in a cool, dry place, away from direct sunlight.

• After reconstitution, store as per label instructions and use within the recommended period.

• Keep out of reach of children.